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- 1905
- Missionary Dr. J. W. Nolan, the first director, opened Kwangju Jejungwon on November 20.
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- 1908
- Missionary Dr. R. M. Wilson became the second director.
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- 1911
- Ellen-Lavine Graham Hospital was built.
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- 1912
- A leper colony was built.
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- 1923
- A dental office was opened by missionary Dr. J. K. Levie.
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- 1930
- Missionary Dr. L. C. Brand became the third director and devoted himself to the elimination of tuberculosis.
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- 1933
- Ellen-Lavine Graham Hospital was destroyed by a fire.
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- 1934
- A two-story fire proof building with a central heating system was constructed to continue mission works.
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- 1940
- Missionary Dr. J. F. Preston, Jr. became the fourth director. In November, Ellen-Lavine Graham Hospital was closed by the Japanese Empire.
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- 1951
- Missionary Dr. H. A. Codington was appointed as the fifth director in September and reopened the hospital.
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- 1955
- A new tuberculosis ward was built.
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- 1963
- Missionary Dr. D. H. Neuisma reopened dental office.
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- 1965
- Ellen-Lavine Graham Hospital was accredited as an intern training and general hospital.
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- 1966
- Missionary Dr. W. L. Simpson became the sixth director.
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- 1967
- Missionary Dr. R. B. Dietrick was appointed as the seventh director.
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- 1976
- Dr. Chin Duk Huh became the eighth director. He was the first Korean director.
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- 1988
- A Mother-Child Health Center was built.
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- 1991
- The Emergency Center and Health Screening Center were newly built.
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- 1996
- Dr. Ki Bok Kim became the ninth director.
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- 1998
- Dr. Ju Sup Park became the tenth director.
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- 2000
- The Order Communication System(OCS) was developed.
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- 2001
- The Operating Room, Wilson Hall, Intensive Care Unit, Labor Room, NICU, Engine Room, and Transformer Substation were extended and moved to their present locations.
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- 2002
- Dr. Kyung Euy Song became the eleventh director.
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- 2003
- The Hospice ward was newly opened.
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- 2004
- Gastrointestinal Endoscopy Center and Micro Reconstructive Surgery Center were newly opened.
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- 2005
- Day Surgery Center was newly opened. The hospital celebrated itsCentennial Anniversary with old missionaries and their families.
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- 2006
- Children Rehabilitation Center was newly opened.
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- 2007
- Dr. Byung Ran Park became the twelfth director.
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- 2009
~2011
- Remodeling of the hospital.
At present, the total land area of the hospital is 37,873㎡, and the total hospital building site is 43,574㎡. The hospital building has 600 beds. There are about 800 hospital staff and 28 medical departments.